The superior sagittal sinus runs along the midline of the skull, extending from the frontal bone to the occipital bone. It is located in the space between the dura mater, which is the outermost protective layer of the brain, and the skull. This sinus begins at the crista galli, a small projection of bone at the front of the skull, and terminates at the confluence of the sinuses, where it joins the transverse sinuses. The positioning of the superior sagittal sinus allows it to effectively gather venous blood from both the left and right hemispheres, seamlessly integrating into the larger venous drainage system of the brain.