The primary functions of stratified columnar epithelium are protection and secretion. This tissue safeguards underlying structures from mechanical and chemical stresses, while its columnar cells play a significant role in secreting mucus and other substances. Found in regions where two different types of epithelia meet, stratified columnar epithelium not only serves as a protective layer but also helps facilitate the transport of materials, thus maintaining the health and function of the underlying tissues. Additionally, this epithelium can be involved in absorption processes and the protection of underlying tissues against pathogens.
Stratified columnar epithelium is most commonly found in specific parts of the body, such as the male urethra, large ducts of some glands (like the salivary and sweat glands), and portions of the pharynx. In these locations, the epithelium provides an essential protective barrier while permitting the passage of substances, ensuring the functionality of these regions. This epithelium usually sits above a layer of cuboidal or columnar cells, contributing to its stratified nature. Its placement in areas that undergo wear and tear exemplifies its crucial role in the body's defense system.