The primary function of mesothelial tissue is to provide a smooth, frictionless surface for organs, particularly those within the pleural, pericardial, and peritoneal cavities. This unique tissue helps to minimize friction between visceral and parietal layers as organs expand and contract, such as during breathing or digestion. Additionally, mesothelial cells secrete serous fluid that serves as a lubricant and protective medium, assisting in organ mobility and reducing the risk of inflammation or injury. The mesothelium also plays a role in immune responses by acting as a physical barrier and facilitating the movement of immune cells to sites of infection or injury, thus contributing to the body’s overall health and maintenance.
Mesothelial tissue is found lining various serous cavities in the body. It can be located in the pleural cavities surrounding the lungs, the pericardial cavity surrounding the heart, and the peritoneal cavity lining the abdominal organs. This tissue forms a continuous layer over the surfaces of these cavities and is integral to the functioning of several organ systems. In the pleura, it creates a double-layer membrane with the parietal pleura lining the thoracic cavity and the visceral pleura covering each lung. The pericardial mesothelium follows a similar pattern around the heart, while peritoneal mesothelium lines the abdominal cavity and envelops most abdominal organs, creating a protective environment that allows for organ movement and interaction.