The primary function of simple squamous epithelium is to facilitate the processes of diffusion and filtration. Its thin structure allows substances such as gases, nutrients, and waste products to pass through with ease. For instance, in the alveoli of the lungs, oxygen and carbon dioxide diffuse across this epithelium during respiration. In the capillary walls, simple squamous epithelium ensures the efficient exchange of materials between blood and tissues. Additionally, this epithelium plays a role in providing a smooth surface for organs to reduce friction during movement, which is particularly important within body cavities that require fluid movement.
Simple squamous epithelium is found in various locations throughout the body, particularly in places requiring rapid transport of substances. It lines the alveoli of the lungs, allowing for gas exchange. This tissue type also forms the endothelium, the thin layer of cells lining blood vessels, and the mesothelium, which lines the body cavities. It can be found in the glomeruli of the kidneys, contributing to the filtration of blood, as well as covering certain parts of the serous membranes, such as the pleura and peritoneum, providing a slick surface that reduces friction between organs.